Brilliant Minds — Season 2
20 episodesFirst aired 21 September 2025
Seeing people, not patients. Zachary Quinto returns as Dr. Wolf, a brilliant neurologist at Bronx General whose compassionate approach leads to astounding breakthroughs in some of the world’s most puzzling psychological cases.
E1The Phantom Hook
4.0Sept 202543m
Dr. Wolf helps an MMA fighter with mysterious symptoms. Dr. Pierce considers a career outside of Bronx General.
E2The Contestant
4.0Sept 202543m
A reality show contestant lands at the hospital with an unusual delusion. Dr. Pierce fights for her future at Bronx General.
E3The Pusher
5.0Oct 202543m
Dr. Wolf and his team treat a young patient accused of a serious crime.
E4Lady Liberty
8.0Oct 202543m
Dr. Wolf and Dr. Pierce are tasked with a house call to evaluate a woman under a conservatorship. Dr. Kinney's curiosity is piqued by a patient outside the hospital.
E5Once Upon a Time in America
7.0Oct 202543m
When two patients arrive in critical condition, Dr. Wolf and Dr. Nichols must do whatever it takes to keep them alive.
E6The Doctor's Graveyard
8.0Oct 202543m
Dr. Wolf is haunted by a ghost from his past. A patient arrives at Bronx General who appears to have risen from the dead.
E7The One That Got Away
8.0Nov 202543m
A blast from the past shakes up Dr. Wolf's world when he becomes his next patient.
E8The Upside Down
8.5Nov 202543m
On a flight gone wrong, one patient's life is literally turned upside down.
E9The Fire Fighter
8.2Nov 202543m
Wolf treats a heroic firefighter who struggles to share his ALS diagnosis with his family.
E10The Resident
8.8Dec 202542m
Dr. Wolf helps a ballerina recover after a mystery illness; the team tries to save Sam's life and get him on the transplant list; secrets are revealed at the hospital's annual holiday gala that change the course of the doctors' lives.
E11The Boy Who Feels Everything
10.0Jan 202642m
Dr. Wolf and the team come together as one of their own fights for their life.
E12The Rider
8.5Jan 202642m
A rugged cowboy struts into Bronx General with mysterious symptoms and brings the rodeo with him; Dr. Wolf develops a relationship with someone who has ties to his father.
E13The Rabbit Hole
Jan 202641m
When a college student comes in with a life-threatening illness, Dr. Wolf and his team have to get acquainted with sorority life. Dr. Thorne treats a child who collapsed under mysterious circumstances.
E14The Invisible Man
8.0Feb 202642m
A grisly accident puts everyone at Bronx General in danger and leads to a shocking revelation about Dr. Wolf.
E15The Missing Person
May 202642m
A Party Girl, who's on the run, is rushed into the hospital and our doctors have to figure out what exactly she's running from. When Wolf doesn't show up for his shift at the hospital, Carol-- worried about his mental health-- goes on a mission to find him.
E16Senses
8.5Jun 202640m
Wolf grapples with being a psych patient at Hudson Oaks and has a startling revelation. A renowned chef comes into Bronx General after a harrowing accident at his restaurant.
E17Doctor, Interrupted
Jun 202642m
Wolf becomes fascinated with an unusual patient at Hudson Oaks, who displays signs of being possessed. Carol and Thorne help newlyweds who are struggling with their sex life.
E18Through the Looking Glass
Jun 202642m
On his first day back at Bronx General, Wolf treats an ex-con who has a medical emergency during a hostage situation; Ericka and Charlie care for a newborn baby in the midst of a life-threatening illness.
E19The Hero's Journey
Jun 202642m
Wolf treats an anxious teen boy who's faced with a terrifying procedure: awake brain surgery. Carol and Dana investigate possible corruption at Hudson Oaks.
E20The Way Home
10.0Jul 202642m
Wolf and Josh’s relationship is tested when they tackle a case that hits close to home. Carol and Thorne deal with their own medical mystery: a patient harboring a huge secret. Van returns and helps Ericka and Dana through their own personal crises.