43 episodesFirst aired 29 August 2015
E1Aug 201550m
Jacob institutes emergency protocol after gang violence takes a deadly turn.
E2Aug 20151h
Tensions rise, and gang crime threatens to spill in to the hospital corridors.
E3Sept 201550m
It's a big day for Louise as an unusual romance flourishes at Holby ED.
E4Sept 201550m
There's a new doctor in the ED as life and death hang in the balance.
E5Sept 201550m
Terror comes to Holby, and the innocent get caught in the crossfire.
E6Oct 201550m
Iain and Dixie are pushed to the limit, but their rewards are many.
E7Oct 201550m
Cal's back on an even keel. Can things only get better?
E8Oct 201550m
Charlie helps a father and daughter deal with their grief.
E9Oct 201550m
Jacob helps a harassed teacher to accept help, but can he take his own advice?
E10Oct 201550m
Things get fishy when an unlikely patient comes into the ED.
E11Nov 201550m
Alicia is pushed to her limits and proves she's a brilliant doctor, but will it be enough?
E12Nov 201550m
Dixie is forced to ignore her gut feeling, and Cal faces every parent's nightmare.
E13Nov 201550m
A young couple have their wedding torn apart by an unsupportive father.
E14Dec 201550m
The harsh conditions of the season bring some people together, but others are torn apart.
E15Dec 201550m
Connie dismisses Jacob's correct instincts.
E16Dec 201550m
It's Christmas Eve and spirits are high, but not everyone is feeling merry.
E17Jan 201650m
Cal struggles with his recent discovery but discovers he's much braver than he thinks.
E18Jan 201650m
Dixie steps up as the hero but is left feeling bittersweet.
E19Jan 201650m
The ED is pushed to the limit, but the team pull together under difficult circumstances.
E20Jan 201650m
Jacob teaches a hopeless man how to approach his crush, while Ethan becomes disillusioned.
E21Jan 201650m
Dixie helps a man face the truth but will she make the right decision about her own life?
E22Feb 201650m
Ethan is back in full swing, but his world is about to be shaken.
E23Feb 201650m
It's Valentine's Day and not everyone is feeling the love.
E24Feb 201650m
Connie needs to step up and prove her love for Grace, but the clock is ticking.
E25Feb 201650m
As Lofty gets the hang of his new role, could a fatal error make his victory short-lived?
E26Mar 201650m
Lofty has to make a statement. With his friends' support, what will he decide to say?
E27Mar 201650m
Lofty faces the consequences of his actions and has a life-changing decision to make.
E28Mar 201650m
Connie's ready to say yes to love, but there's just one person she needs to tell first.
E29Apr 201650m
Connie is faced with the prospect of never seeing Grace again.
E30Apr 201650m
Jacob takes it upon himself to track down a dangerous drug dealer in Holby.
E31Apr 201650m
Rita gets the shock of her life when a ghost from her past arrives at the ED.
E32Apr 201650m
Big Mac's secret is getting on top of him.
E33Apr 201650m
Fate forces Max and Zoe to work as a team, whilst a poisonous spider gets loose in Holby.
E34May 201650m
A new doctor starts at the emergency department and she is about to get a baptism of fire.
E35May 201650m
Dylan gets a nasty surprise when a familiar face arrives asking for forgiveness.
E36May 201650m
Big Mac struggles to hide the toll his addiction is taking.
E37Jun 201650m
Elle is forced into a corner after a shocking discovery.
E38Jun 201650m
Can Big Mac overcome his demons and help a young girl in need?
E39Jun 201650m
Elle tries to save the life of a mother and her unborn child.
E40Jul 201650m
Jacob shows some uncharacteristic nerves, while Rita gets caught up in her own lies.
E41Jul 201650m
Dylan treats his family, while David uncovers Glen's secret.
E42Jul 201650m
Rita gets a frosty reception from the ED, while Iain struggles to assert his authority.
E43Jul 201650m
Connie deals with a case too close to home; will she and Grace find a way through?